Spravato® (esketamine) Nasal Therapy

A breakthrough treatment for depression that targets the brain differently — offering new hope when traditional medications haven’t worked.
Spravato

Spravato® is an FDA-approved nasal spray designed for adults with treatment-resistant depression (TRD) or major depressive disorder (MDD) with suicidal thoughts.

Unlike traditional antidepressants that work over weeks, Spravato® acts on the brain’s glutamate system — promoting new neural connections and restoring balance faster.

At InnerCalm Wellness, our Spravato® sessions are guided by trained clinicians who ensure comfort, safety, and support during every treatment.
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How Spravato® works

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Targets Glutamate System

Spravato® increases activity in NMDA receptors — helping restore balance in brain areas responsible for mood, motivation, & emotion.

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Promotes Neural Growth

The treatment encourages new connections between neurons, supporting long-term mood stabilization and emotional resilience.
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Works Alongside Oral Medication

Spravato® can be used with an oral antidepressant under close clinical supervision to ensure safety and effectiveness.
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What To Expect

Arrival & Check-In:

A clinician reviews your vitals and guides you through the process.

Spravato® Administration:

You self-administer the nasal spray under supervision.

Observation Period:

You’ll relax in a reclined chair for about two hours as we monitor your response.

Post-Treatment Review:

Before discharge, we review your experience, track your progress, and plan your next visit. You’ll need a ride home after each session - driving isn’t allowed the same day.

What Our Patients Say

Frequently Asked Questions

Common questions about TMS therapy, Spravato®, and our mental health services in NY & NJ

What is TMS therapy and is it effective for depression?

TMS (Transcranial Magnetic Stimulation) is an FDA-cleared, non-invasive brain stimulation therapy for treatment-resistant depression. Clinical studies show 50-60% of patients experience significant improvement, with about 1 in 3 achieving full remission. InnerCalm Wellness offers TMS at all three NY & NJ locations.

Yes — InnerCalm Wellness is proud to be a Tricare East provider, covering active duty military, veterans, and their families in New York and New Jersey. We also accept most major commercial insurance plans.
Spravato (esketamine) is an FDA-approved nasal spray for treatment-resistant depression administered under medical supervision in our clinic. It works rapidly — often within hours — and is ideal for patients who haven’t responded to two or more antidepressants. Ask our team if you qualify.

Our IOP provides structured, evidence-based therapy several days per week without requiring full hospitalization. It’s ideal for patients who need more support than weekly therapy but don’t require inpatient care — treating depression, anxiety, PTSD, and substance use disorders in Queens NY and surrounding areas.

InnerCalm Wellness has three convenient locations: Hicksville, NY (serving Long Island — Nassau County, Suffolk County), Jamaica, NY (serving Queens, Brooklyn, and surrounding NYC boroughs), and Jersey City, NJ (serving Hudson County and greater Northern New Jersey).

You can book online 24/7 using our patient portal, or call (516) 513-1256. Hicksville: Ext. 203 | Jamaica: Ext. 501 | Jersey City: Ext. 802. New patients are welcome and most insurance is accepted.

Ready to Start Your Healing Journey?

Book your consultation today — no referral needed. We accept most major insurance plans including Tricare East.