Spravato® (esketamine) Nasal Therapy

A breakthrough treatment for depression that targets the brain differently — offering new hope when traditional medications haven’t worked.
Spravato

Spravato® is an FDA-approved nasal spray designed for adults with treatment-resistant depression (TRD) or major depressive disorder (MDD) with suicidal thoughts.

Unlike traditional antidepressants that work over weeks, Spravato® acts on the brain’s glutamate system — promoting new neural connections and restoring balance faster.

At InnerCalm Wellness, our Spravato® sessions are guided by trained clinicians who ensure comfort, safety, and support during every treatment.
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How Spravato® works

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Targets Glutamate System

Spravato® increases activity in NMDA receptors — helping restore balance in brain areas responsible for mood, motivation, & emotion.

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Promotes Neural Growth

The treatment encourages new connections between neurons, supporting long-term mood stabilization and emotional resilience.
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Works Alongside Oral Medication

Spravato® can be used with an oral antidepressant under close clinical supervision to ensure safety and effectiveness.
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What To Expect

Arrival & Check-In:

A clinician reviews your vitals and guides you through the process.

Spravato® Administration:

You self-administer the nasal spray under supervision.

Observation Period:

You’ll relax in a reclined chair for about two hours as we monitor your response.

Post-Treatment Review:

Before discharge, we review your experience, track your progress, and plan your next visit. You’ll need a ride home after each session - driving isn’t allowed the same day.

What Our Patients Say

Frequently Asked Questions

Common questions about TMS therapy, Spravato®, and our mental health services in NY & NJ

What is TMS therapy and is it effective for depression?

TMS (Transcranial Magnetic Stimulation) is an FDA-cleared, non-invasive brain stimulation therapy for treatment-resistant depression. Clinical studies show 50-60% of patients experience significant improvement, with about 1 in 3 achieving full remission. InnerCalm Wellness offers TMS at all three NY & NJ locations.

Yes — InnerCalm Wellness is proud to be a Tricare East provider, covering active duty military, veterans, and their families in New York and New Jersey. We also accept most major commercial insurance plans.
Spravato (esketamine) is an FDA-approved nasal spray for treatment-resistant depression administered under medical supervision in our clinic. It works rapidly — often within hours — and is ideal for patients who haven’t responded to two or more antidepressants. Ask our team if you qualify.

Our IOP provides structured, evidence-based therapy several days per week without requiring full hospitalization. It’s ideal for patients who need more support than weekly therapy but don’t require inpatient care — treating depression, anxiety, PTSD, and substance use disorders in Queens NY and surrounding areas.

InnerCalm Wellness has four convenient locations: Hicksville, NY (serving Long Island — Nassau County, Suffolk County), Jamaica, NY (serving Queens, Brooklyn, and surrounding NYC boroughs), Harlem, NY (serving Manhattan and the Bronx), and Jersey City, NJ (serving Hudson County and greater Northern New Jersey).

You can book online 24/7 using our patient portal, or call (516) 513-1256. Hicksville: Ext. 203 | Jamaica: Ext. 501 | Harlem: Ext. 401 | Jersey City: Ext. 802. New patients are welcome and most insurance is accepted.

Ready to Start Your Healing Journey?

Book your consultation today — no referral needed. We accept most major insurance plans including Tricare East.