Spravato® (Esketamine) Nasal Therapy

A non-invasive, medication-free therapy that restores healthy brain activity for people struggling with depression, anxiety, and OCD.

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Spravato® is an FDA-approved nasal spray designed for adults with treatment-resistant depression (TRD) or major depressive disorder (MDD) with suicidal thoughts.

Unlike traditional antidepressants that work over weeks, Spravato® acts on the brain’s glutamate system — promoting new neural connections and restoring balance faster.

At InnerCalm Wellness, our Spravato® sessions are guided by trained clinicians who ensure comfort, safety, and support during every treatment.

Esketamine

How Spravato® works

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Targets Glutamate System
Spravato® increases activity in NMDA receptors — helping restore balance in brain areas responsible for mood, motivation, & emotion.
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Promotes Neural Growth

The treatment encourages new connections between neurons, supporting long-term mood stabilization and emotional resilience.

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Works Alongside Oral Medication
Spravato® can be used with an oral antidepressant under close clinical supervision to ensure safety and effectiveness.

What To Expect

Arrival & Check-In:

A clinician reviews your vitals and guides you through the process.

Spravato® Administration:

You self-administer the nasal spray under supervision.

Observation Period:

You’ll relax in a reclined chair for about two hours as we monitor your response.

Post-Treatment Review:

Before discharge, we review your experience, track your progress, and plan your next visit. You’ll need a ride home after each session – driving isn’t allowed the same day.

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What Our Patients Say

Frequently Asked Questions

Common questions about TMS therapy, Spravato®, and our mental health services in NY & NJ

What is TMS therapy and is it effective for depression?

TMS (Transcranial Magnetic Stimulation) is an FDA-cleared, non-invasive brain stimulation therapy for treatment-resistant depression. Clinical studies show 50-60% of patients experience significant improvement, with about 1 in 3 achieving full remission. InnerCalm Wellness offers TMS at all three NY & NJ locations.

TMS (Transcranial Magnetic Stimulation) is an FDA-cleared, non-invasive brain stimulation therapy for treatment-resistant depression. Clinical studies show 50-60% of patients experience significant improvement, with about 1 in 3 achieving full remission. InnerCalm Wellness offers TMS at all three NY & NJ locations.

TMS (Transcranial Magnetic Stimulation) is an FDA-cleared, non-invasive brain stimulation therapy for treatment-resistant depression. Clinical studies show 50-60% of patients experience significant improvement, with about 1 in 3 achieving full remission. InnerCalm Wellness offers TMS at all three NY & NJ locations.

TMS (Transcranial Magnetic Stimulation) is an FDA-cleared, non-invasive brain stimulation therapy for treatment-resistant depression. Clinical studies show 50-60% of patients experience significant improvement, with about 1 in 3 achieving full remission. InnerCalm Wellness offers TMS at all three NY & NJ locations.

TMS (Transcranial Magnetic Stimulation) is an FDA-cleared, non-invasive brain stimulation therapy for treatment-resistant depression. Clinical studies show 50-60% of patients experience significant improvement, with about 1 in 3 achieving full remission. InnerCalm Wellness offers TMS at all three NY & NJ locations.

Ready to Start Your Healing Journey?

Book your consultation today — no referral needed. We accept most major insurance plans including Tricare East.